Cyclopentolate is an anticholinergic drug, which is used as a cycloplegic in eye examinations for mydriasis.Though rare, if absorbed systematically, it is known to cause central anticholinergic syndrome. Children are especially prone to this due to their lower body weight. Central anticholinergic syndrome (CAS) is a clinical entity which shows central and peripheral effects produced by over dosage or abnormal reaction to clinical dosage of anticholinergic drugs. Anxiety, seizures, tachycardia, hyperpyrexia, mydriasis, vasodilatation, gastric and urinary retention can be observed during CAS. We may also see behavioral changes and transient psychotic reactions. Here we are reporting a case of a 7- year- old female child who after instillation of cyclopentolate eye drops developed psychosis. The Child was kept under observation for about 24 hours and her symptoms remitted spontaneously.
Keywords: Psychosis, Cyclopentolate, Central anticholinergic syndrome.